Author

Sophie Leboulleux

University Hospital of GenevaORCID 0000-0002-0771-3033Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Abir Al GhuzlaniD· 1 shared Camille BuffetiD· 1 shared Caroline Coelho de FariaiD· 1 shared Catline NobreiD· 1 shared Corinne DupuyiD· 1 shared Floriane BrayéiD· 1 shared Juliana CazariniD· 1 shared Karine Godefroy· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Abir Al GhuzlanORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

NOX4 prevents the recruitment of PAX8 and NKX2.1 to chromatin in BRAF-mutated thyroid cancer cells.

Mickaëlle Radom, Camille Buffet, Juliana Cazarin, Marylin Harinquet, Caroline Coelho de Faria, Floriane Brayé, Catline Nobre, Marine Aglave, Yasmina Mesloub, Thibault Dayris, Nathalie M Droin, Karine Godefroy, Mohamed Amine Bani, Abir Al Ghuzlan, Sophie Leboulleux, , Corinne Dupuy

The paper shows that NOX4-generated ROS repress NIS in BRAFV600E-mutated thyroid cancer cells by blocking PAX8 and NKX2.1 chromatin binding through DNA damage and epigenetic mechanisms.

bioRxiv · Apr 14, 2025 · PreprintCancer Biology