Juliana Cazarin

This study identifies Dec2 as a circadian gene that promotes pancreatic cancer dormancy by reducing MHC-I antigen presentation, enabling immune evasion.

This study shows that extracellular glutathione supports tumor growth by providing amino acids through catabolism, and inhibiting this process slows tumor growth.

This study identifies MYC expression and a mesenchymal cell state as independent predictors of circadian rhythm disruption in lung adenocarcinoma.

The paper shows that NOX4-generated ROS repress NIS in BRAFV600E-mutated thyroid cancer cells by blocking PAX8 and NKX2.1 chromatin binding through DNA damage and epigenetic mechanisms.

This study shows that the tumor microenvironment alters macrophage circadian rhythms, affecting tumorigenesis and macrophage function.