Author

Sitaram Gayatri

Northwestern UniversityORCID 0000-0002-0773-6278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Adrian Lange· 1 shared Andrew L. FergusoniD· 1 shared Anthony Beardsworth CostaiD· 1 shared Benjamin M. LortoniD· 1 shared Brendan P. O’Hara· 1 shared Byoung-Kyu ChoiD· 1 shared Claire M. BuchananiD· 1 shared Claire M. PhoumyvongiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperSynthetic Biology

Adrian Lange

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3 papers

Recent·Most cited

Synthetic BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 6, 2025

ProT-VAE: Protein Transformer Variational AutoEncoder for Functional Protein Design

Emre Sevgen, Joshua Moller, Adrian Lange…·Andrew L. Ferguson

ProT-VAE designs functional proteins by learning sequence-function relationships using a transformer-based variational autoencoder, enabling conditional generation of novel sequences with high functionality.

54 citationstop 1%

protein sequencevariational autoencoder

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GeneticsProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2022

Coessential Genetic Networks Reveal the Organization and Constituents of a Dynamic Cellular Stress Response

David R. Amici, Daniel J. Ansel, Kyle A. Metz…·Marc L. Mendillo

The paper constructs a coessential genetic network to map the dynamic cellular stress response across 625 cancer cell lines, identifying key regulators and modules involved in stress resilience.

30 citations

humanwhole-genome sequencing

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Molecular BiologyiSciencePeer-reviewedAug 11, 2021

Transcriptomic and proteomic regulation through abundant, dynamic, and independent arginine methylation by Type I and Type II PRMTs

Maxim I. Maron, Stephanie M. Lehman, Sitaram Gayatri…·David Shechter

The paper investigates the substrate preferences and functional consequences of Type I and II PRMTs by inhibiting them in A549 cells and analyzing proteomic and transcriptomic changes.

51 citations

humanproteomics

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