Author

Daniel J. Ansel

Northwestern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

David R. AmiciiD· 2 shared Jian LiiD· 2 shared Marc L. MendilloiD· 2 shared Aleksandra Fesiuk· 1 shared Benjamin F. MilleriD· 1 shared Brendan P. O’Hara· 1 shared Byoung-Kyu ChoiD· 1 shared Claire M. PhoumyvongiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

David R. AmiciORCID

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Author profile →

2 papers

Recent·Most cited

HSF1 remodels mitochondrial biogenesis and function in cancer cells via TIMM17A

Ngoc G.T. Nguyen, Hem Sapkota, Yoko Shibata, Aleksandra Fesiuk, Matthew D. Antalek, Vibhavari Sail, Daniel J. Ansel, David R. Amici, Frederick F. Peelor, Holly Van Remmen, Benjamin F. Miller, Marc L. Mendillo, Richard I. Morimoto, Jian Li

This study identifies TIMM17A as a key mediator of HSF1-driven mitochondrial biogenesis and function in cancer cells, revealing a mechanism linking HSF1 to mitochondrial protein import and energy production.

bioRxiv · May 12, 2025 · PreprintCell Biology

Coessential Genetic Networks Reveal the Organization and Constituents of a Dynamic Cellular Stress Response

David R. Amici, Daniel J. Ansel, Kyle A. Metz, Roger S. Smith, Claire M. Phoumyvong, Sitaram Gayatri, Tomasz Chamera, Stacey L. Edwards, Brendan P. O’Hara, Shashank Srivastava, Sonia Brockway, Seesha R. Takagishi, Byoung-Kyu Cho, Young Ah Goo, Neil L. Kelleher, , Marc L. Mendillo

The paper constructs a coessential genetic network to map the dynamic cellular stress response across 625 cancer cell lines, identifying key regulators and modules involved in stress resilience.

Proceedings of the National Academy of Sciences · Jul 1, 2022Peer-reviewedGenetics