Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy
Amulya Sreekumar, Eric R. Blankemeyer, Christopher J. Sterner, Tien-Chi Pan, Dhruv K. Pant, Sarah Acolatse, Hamza Turkistani, George K. Belka, Anupma Nayak, Sean Carlin, Charles‐Antoine Assenmacher, Mark A. Sellmyer, David A. Mankoff, Lewis A. Chodosh
This study identifies SOX5 as a key factor enabling residual breast cancer cells to maintain dormancy through endochondral ossification, improving recurrence-free survival.
Cancer Discovery · Dec 10, 2025Peer-reviewedCancer Biology