Author

Amulya Sreekumar

University of PennsylvaniaORCID 0000-0003-0462-0015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:mouse· 1

Frequent Co-Authors

Lewis A. ChodoshiD· 2 shared Tien-Chi PaniD· 2 shared Anupma NayakiD· 1 shared Brian Benz· 1 shared Charles‐Antoine AssenmacheriD· 1 shared Christopher J. SterneriD· 1 shared Christopher Sterner· 1 shared David A. MankoffiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Lewis A. ChodoshORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Loss of Ferroptosis-suppressors Accelerates Breast Cancer Recurrence by Promoting Dormancy Exit

Emily K. Shea, Matthew Lawrence-Paul, Amulya Sreekumar…·Lewis A. Chodosh

This study identifies PNPLA2, GOT1, and GPX4 as ferroptosis-suppressors whose loss accelerates breast cancer recurrence by promoting dormancy exit and enhancing ferroptosis resistance in dormant cells.

DOI 10.64898/2026.10.22.761187

mousehuman

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Cancer BiologyCancer DiscoveryPeer-reviewedDec 10, 2025

Residual Breast Cancer Cells Co-opt SOX5-driven Endochondral Ossification to Maintain Dormancy

Amulya Sreekumar, Eric R. Blankemeyer, Christopher J. Sterner…·Lewis A. Chodosh

This study identifies SOX5 as a key factor enabling residual breast cancer cells to maintain dormancy through endochondral ossification, improving recurrence-free survival.

1 citation

humanbulk RNA-seq

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