Lewis A. Chodosh

This study identifies PNPLA2, GOT1, and GPX4 as ferroptosis-suppressors whose loss accelerates breast cancer recurrence by promoting dormancy exit and enhancing ferroptosis resistance in dormant cells.

This study identifies SOX5 as a key factor enabling residual breast cancer cells to maintain dormancy through endochondral ossification, improving recurrence-free survival.

This study shows that hypercalcemia from tumor-secreted PTHrP activates hindbrain circuits linked to anorexia, and blocking hypercalcemia prevents these effects.