Author

Tim Beaumont

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-0778-8027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Denise GuerraiD· 2 shared Marit J. van GilsiD· 2 shared Rogier W. SandersiD· 2 shared Andreas Chrysostomou· 1 shared Andrew B. WardiD· 1 shared Gius KersteriD· 1 shared Godelieve J. de BreeiD· 1 shared Jacqueline van Rijswijk· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Denise GuerraORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 30, 2025

A dynamic activation-memory cycle organizes the human IgG⁺ memory B cell compartment

Laura T. M. Graus, Andreas Chrysostomou, Denise Guerra…·Mathieu A. F. Claireaux

This study defines the dynamic activation-memory cycle of human IgG memory B cells through single-cell profiling, revealing distinct reactivation trajectories and functional roles in humoral immunity.

DOI 10.1101/2025.10.30.685644

humanscRNA-seq

𝕏 PostBluesky

MicrobiologyHuman Vaccines & ImmunotherapeuticsPeer-reviewedAug 20, 2024

Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain

Denise Guerra, Laura Radić, Mitch Brinkkemper…·Tim Beaumont

This study develops bispecific antibodies that target conserved regions on the SARS-CoV-2 spike protein, showing improved neutralization breadth against multiple sarbecovirus strains.

3 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky