Mathieu A. F. Claireaux

The paper evaluates adjuvant effects on immune responses in virosome-based SARS-CoV-2 vaccines, finding distinct impacts on humoral and cellular immunity.

This study shows that 3D tonsil cultures with stromal cells enhance antigen-specific B cell responses compared to 2D cultures and improve follicle-like structure formation.

The paper characterizes early antigen-specific B cell responses after vaccination, identifying distinct clusters with different contraction dynamics and potential roles in memory B cell formation.

This study defines the dynamic activation-memory cycle of human IgG memory B cells through single-cell profiling, revealing distinct reactivation trajectories and functional roles in humoral immunity.

This paper describes an experimental pipeline for generating human monoclonal antibodies against bacterial pathogens using synthetic glycan fragments, identifying functional antibodies against Staphylococcus aureus and Streptococcus pyogenes.

This study shows that fusing C3d to HIV-1 Env immunogens enhances germinal center responses and improves vaccine immunogenicity.

The paper identifies novel stages in IgG memory B cell and antibody-secreting cell differentiation by analyzing antigen-specific B cells from different pathogens using high-dimensional flow cytometry.