Author

Fabian M Bock

United States Department of Veterans AffairsORCID 0000-0002-0788-2945Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Roy ZentiD· 3 shared Ambra PozziiD· 2 shared Louise LantieriD· 2 shared Meiling MelzeriD· 2 shared Olga M. ViqueziD· 2 shared Xinyu DongiD· 2 shared A. Scott McCalliD· 1 shared Ahmed ElwakieliD· 1 shared

Activity by Year

2021-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPhysiology

Roy ZentORCID

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Author profile →

4 papers

Recent·Most cited

α-Parvin regulation of cell re-arrangement is critical for ureteric bud branching morphogenesis

Xinyu Dong, Fabian M Bock, Ali Hashmi, Nada M. Bulus, Glenda Mernaugh, Gema Bolás, Shensen Li, Wanying Zhu, Meiling Melzer, Kyle L. Brown, Colton Miler, Olga M. Viquez, Eloi Montañez, Ambra Pozzi, Sara A. Wickström, Roy Zent

This study shows that α-parvin regulates cell rearrangements during ureteric bud branching by inhibiting cell adhesion and actin polymerization.

Science Advances · Sep 18, 2026Peer-reviewedDevelopmental Biology

Dehydration promotes intracellular lipid synthesis and accumulation

Joshua Carty, Jazlyn A. Selvasingh, Yvonne P. Zuchowski, Hyuck-Jin Nam, Clothilde Pénalva, Gayani Nanayakkara, Erin Q. Jennings, Kelsey Voss, Edith T. Adame, John T. Tossberg, Wei Sheng Yap, Meiling Melzer, Olga M. Viquez, A. Scott McCall, Elizabeth R. Piotrowski, , Juan Pablo Arroyo

This study shows dehydration increases intracellular lipid synthesis and accumulation by promoting glutamine oxidation and mitochondrial metabolic remodeling.

Nature Communications · May 25, 2026Peer-reviewedPhysiology

Alpha Parvin Promotes Glucose Uptake and Metabolism in Skeletal Muscle with Minimal Influence on Hepatic Insulin Sensitivity

Fabian M Bock, Xinyu Dong, Kakali Ghoshal, David A. Cappel, John William Deaver, Dan Lark, Luciano Cozzani, Deanna P. Bracy, Louise Lantier, Allison DO, Richard L. Printz, Santosh Thapa, Owen P. McGuinness, David H. Wasserman, Ambra Pozzi, , Nathan C. Winn

This study shows that Parvin in skeletal muscle is essential for insulin-stimulated glucose uptake and mitochondrial function, while having little effect on liver insulin sensitivity.

Molecular Metabolism · Jan 21, 2026Peer-reviewedPhysiology

Reversal of the renal hyperglycemic memory by targeting sustained tubular p21 expression

Moh’d Mohanad Al‐Dabet, Khurrum Shahzad, Ahmed Elwakiel, Alba Sulaj, Stefan Kopf, Fabian M Bock, Ihsan Gadi, Silke Zimmermann, Rajiv Rana, Shruthi Krishnan, Dheerendra Gupta, Sumra Nazir, Ronny Baber, Markus R. Scholz, Robert Geffers, , Berend Heinrich Isermann

The paper identifies p21 as a key mediator of hyperglycemic memory in diabetic kidney disease and shows that aPC signaling can reverse its effects.

bioRxiv · Jul 5, 2021 · PreprintMolecular Biology