Author

Sophia Nozick

Northwestern UniversityORCID 0000-0002-0791-6340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alan R. HauseriD· 3 shared Egon Anderson OzeriD· 3 shared Preeti GaraiiD· 2 shared Alexander V. MishariniD· 1 shared Alexandra C. McQuattie‐PimenteliD· 1 shared Ali MahmoudiD· 1 shared Aliki ValdesiD· 1 shared Alvaro DonayreiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Alan R. HauserORCID

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Author profile →

3 papers

Recent·Most cited

Comparison of Galleria mellonella, Epithelial Cell Cytotoxicity, and Mouse Model of Bacteremia to Measure Pseudomonas aeruginosa Virulence

Aliki Valdes, Christopher M. R. Axline, Travis J. Kochan, Sophia Nozick, Timothy J. Ward, Issay Niki, Ethan M. VanGosen, David Hynes, Julia Nelson, Preeti Garai, Tania Afzal, Daniel Boris Amusin, Sumitra D. Mitra, Timothy Lee Turner, William Cheng, , Alan R. Hauser

This study compares Galleria mellonella, epithelial cell cytotoxicity, and mouse models for measuring Pseudomonas aeruginosa virulence, finding G. mellonella correlates better with mouse results for population-level trends.

Infection and Immunity · Aug 19, 2026Peer-reviewedMicrobiology

A novel mechanism of ceftolozane-tazobactam resistance in Pseudomonas aeruginosa mediated by L2 β-lactamase

Preeti Garai, Sophia Nozick, Caroline C. Jozefczyk, Hannah H. Nam, J. Nicholas O’Donnell, Egon Anderson Ozer, Alan R. Hauser, Nathaniel J. Rhodes

The paper identifies a novel mechanism of ceftolozane-tazobactam resistance in Pseudomonas aeruginosa mediated by an L2 β-lactamase gene, independent of its canonical regulator.

bioRxiv · Mar 13, 2026 · PreprintMicrobiology

A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia

Nikolay S. Markov, Ziyou Ren, Karolina J. Senkow, Rogan A. Grant, Catherine A. Gao, Elizabeth S. Malsin, Lango Sichizya, Hermon G. Kihshen, Kathryn A. Helmin, Milica Jovisic, Jason M Arnold, Xóchitl G. Pérez-Leonor, Hiam Abdala‐Valencia, Suchitra Swaminathan, Julu Nwaezeapu, , Karen M. Ridge

The paper examines alveolar T cell responses in SARS-CoV-2 pneumonia patients, finding that early interferon signaling and targeting of structural proteins correlate with better clinical outcomes.

Nature Immunology · Aug 13, 2024Peer-reviewedSystems Biology