Ziyou Ren

This study evaluates citrate-based hydrogels for promoting wound closure in infected diabetic wounds, finding that formulations with copper nanoparticles and cell adhesion peptides significantly improve healing.

This study uses scRNA-seq to show Dsg1 coordinates cell proliferation and actin dynamics to drive epidermal morphogenesis through a Dsg1-Nck1-N-WASP axis.

This study identifies declining Wnt signaling as a driver of age-related alveolar stem cell loss and shows that restoring Wnt signaling in aged mice improves lung repair but not full regeneration.

This study investigates how stress exacerbates metabolic and oxidative stress in heterozygous Darier disease, leading to disrupted intercellular adhesion and skin lesions.

The paper examines alveolar T cell responses in SARS-CoV-2 pneumonia patients, finding that early interferon signaling and targeting of structural proteins correlate with better clinical outcomes.

This paper performs RNA-seq on skin samples from three acantholytic diseases to identify shared transcriptomic features and mechanisms of pathogenesis.

The paper develops an information-theory-based method to improve cell type annotation and reproducibility in scRNA-seq analysis by benchmarking feature selection and clustering approaches.

Single-cell RNA-seq of lung tissue from transplant donors, fibrosis patients, and a living patient identifies cell type-specific disease-associated molecular pathways in pulmonary fibrosis.