Alan R. Hauser

This study identifies 13 genes essential for extreme colistin resistance in Pseudomonas aeruginosa using transposon insertion sequencing and validates novel pathways contributing to resistance.

This study compares Galleria mellonella, epithelial cell cytotoxicity, and mouse models for measuring Pseudomonas aeruginosa virulence, finding G. mellonella correlates better with mouse results for population-level trends.

The paper identifies a novel mechanism of ceftolozane-tazobactam resistance in Pseudomonas aeruginosa mediated by an L2 β-lactamase gene, independent of its canonical regulator.

This study models Pseudomonas aeruginosa gastrointestinal carriage in mice using vancomycin pretreatment and identifies the stomach as a major barrier to colonization.

The paper examines alveolar T cell responses in SARS-CoV-2 pneumonia patients, finding that early interferon signaling and targeting of structural proteins correlate with better clinical outcomes.

This paper uses machine learning to predict the virulence of Pseudomonas aeruginosa isolates based on genomic data, achieving 75% accuracy using random forest models.