Author

Silvano Gonzalez

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Arthur Jeremy WillseyiD· 2 shared Belinda WangiD· 2 shared Ethel Bader· 2 shared Helen Rankin WillseyiD· 2 shared Matthew W. StateiD· 2 shared Micaela C. LasseriD· 2 shared Nawei SuniD· 2 shared Sam Drake· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Arthur Jeremy WillseyORCID

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2 papers

Recent·Most cited

A foundational atlas of autism protein interactions reveals molecular convergence

Belinda Wang, Rasika S. Vartak, Yefim Zaltsman, Zun Zar Chi Naing, Kelsey M. Hennick, Benjamin J. Polacco, Ali Bashir, Manon Eckhardt, Mehdi Bouhaddou, Jiewei Xu, Nawei Sun, Micaela C. Lasser, Yuan M. Zhou, Justin McKetney, Keelan Z. Guiley, , Nevan J. Krogan

The paper constructs a PPI network of 100 high-confidence ASD genes, identifies novel interactions, and uses AlphaFold-Multimer to prioritize variants for functional validation in organoids.

bioRxiv · Dec 3, 2023 · PreprintSystems Biology

Pleiotropy of autism-associated chromatin regulators

Micaela C. Lasser, Nawei Sun, Yuxiao Xu, Sheng Wang, Sam Drake, Karen Law, Silvano Gonzalez, Belinda Wang, Vanessa Drury, Octavio Castillo, Yefim Zaltsman, Jeanselle Dea, Ethel Bader, Kate E. McCluskey, Matthew W. State, , Helen Rankin Willsey

The paper investigates the role of chromatin regulators in autism spectrum disorder (ASD) by examining their involvement in microtubule biology and cellular proliferation, finding that ASD risk genes affect these processes and are enriched among microtubule-associated proteins.

Development · Jun 27, 2023Peer-reviewedDevelopmental Biology