Author

Sheng Wang

University of California, San FranciscoORCID 0000-0002-1809-3116Unclaimed ORCID profile · follow to get notified of new preprints

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Sheng Wang7 papers · Chinese Academy of Sciences

Biology Disciplines

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Developmental Biology· 2 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Arthur Jeremy WillseyiD· 3 shared Nawei SuniD· 3 shared Ethel Bader· 2 shared Helen Rankin WillseyiD· 2 shared Jeanselle DeaiD· 2 shared Kate E. McCluskeyiD· 2 shared Matthew W. StateiD· 2 shared Micaela C. LasseriD· 2 shared

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2018-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Arthur Jeremy WillseyORCID

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4 papers

Recent·Most cited

Ciliary biology intersects autism and congenital heart disease

Nia Teerikorpi, Kate E. McCluskey, Ethel Bader, Micaela C. Lasser, Sheng Wang, Catherine H. Nguyen, James D. Schmidt, Elina Kostyanovskaya, Nawei Sun, Jeanselle Dea, Tomasz Jan Nowakowski, Arthur Jeremy Willsey, Helen Rankin Willsey

The paper identifies CHD genes that disrupt NPC biology and are enriched for ciliary biology, linking cilia dysfunction to ASD and CHD comorbidity.

Development · Jun 15, 2025Peer-reviewedDevelopmental Biology

Pleiotropy of autism-associated chromatin regulators

Micaela C. Lasser, Nawei Sun, Yuxiao Xu, Sheng Wang, Sam Drake, Karen Law, Silvano Gonzalez, Belinda Wang, Vanessa Drury, Octavio Castillo, Yefim Zaltsman, Jeanselle Dea, Ethel Bader, Kate E. McCluskey, Matthew W. State, , Helen Rankin Willsey

The paper investigates the role of chromatin regulators in autism spectrum disorder (ASD) by examining their involvement in microtubule biology and cellular proliferation, finding that ASD risk genes affect these processes and are enriched among microtubule-associated proteins.

Development · Jun 27, 2023Peer-reviewedDevelopmental Biology

Rare Maternally Inherited Coding Variants on Chromosome X Carry Predominantly Male Risk in Autism, Tourette Syndrome, and Attention-deficit/Hyperactivity Disorder

Sheng Wang, Belinda Lei Wang, Vanessa Drury, Sam Drake, Nawei Sun, Hasan Alkhairo, Juan Arbelaez, Clif Duhn, Tourette International Collaborative Genetics (TIC Genetics), Vanessa Hus Bal, K. Langley, Joanna Martin, Jinchuan Xing, Gary A. Heiman, Jay A. Tischfield, , Arthur Jeremy Willsey

medRxiv · Sep 22, 2022 · PreprintGenetic & Genomic Medicine

Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs

August Yue Huang, Xiaoxu Yang, Sheng Wang, Xianing Zheng, Qixi Wu, Adam Yongxin Ye, Liping Wei

The paper identifies and characterizes two types of postzygotic single-nucleotide mosaicisms in healthy individuals using whole-genome sequencing across multiple organs.

PLoS Genetics · May 15, 2018Peer-reviewedGenomics