Author

Joachim Rudolph

GenentechORCID 0000-0002-0806-6106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Benjamin T. WaltersiD· 2 shared Aaron LictaoiD· 1 shared Angela XuiD· 1 shared Avi AshkenaziiD· 1 shared Brett M. BabiniD· 1 shared Bridget Hoag· 1 shared Caroline L. GilchristiD· 1 shared Carsten PeukertiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Benjamin T. WaltersORCID

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2 papers

Recent·Most cited

Peroxisome quality control is gated by a dynamic ATF6α-ABCD3 tether

Feng Wang, Rukmini Mukherjee, Carsten Peukert, Thomas G. Laughlin, Jing Wang, Benjamin T. Walters, Tsan‐Wen Lu, Tristan Ian Croll, Deniz Eismann, Shelly Harel, Angela Xu, Kibeom Kim, Meghna Gupta, James J. Crawford, Christopher P. Arthur, , Peter Walter

This paper identifies ATF6α as a non-transcriptional regulator of peroxisome quality control through its interaction with ABCD3, and shows how this interaction can be modulated by Ceapin to influence cancer-related processes.

bioRxiv · Oct 6, 2026 · PreprintCell Biology

Rational design of potent small molecule SMARCA2/A4 (BRM/BRG1) degraders acting via the recruitment of FBXO22

Elisia Villemure, Robert L. Yauch, Joachim Rudolph, Tom Januario, Mingshuo Zeng, Hanna G. Budayeva, Benjamin T. Walters, Aaron Lictao, Sherry K. Li, Xiaofen Ye, Caroline L. Gilchrist, Bridget Hoag, Nicholas Endres, Peter Hsu, John Chan, , Joyce Liu

This paper identifies a potent and specific SMARCA2/A4 degrader, G-6599, which works via FBXO22 recruitment and covalent conjugation, offering therapeutic potential.

bioRxiv · Mar 5, 2025 · PreprintCancer Biology