Author

Xiaofen Ye

GenentechORCID 0009-0001-4465-1839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Robert L. YauchiD· 2 shared Aaron LictaoiD· 1 shared Aaron T. L. LuniD· 1 shared Adrian Waddell· 1 shared Alejandro Martinez ChiblyiD· 1 shared Aleksander ChlebowskiiD· 1 shared Antonina HafneriD· 1 shared Bence DánieliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Robert L. YauchORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedAug 2, 2025

Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state

Tomasz Włodarczyk, Aaron T. L. Lun, Diana H. Wu…·Xiaosai Yao

Epiregulon infers single-cell TF activity using ATAC-seq and RNA-seq to predict drug response and identify drivers of cell state.

13 citations

humanscATAC-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 5, 2025

Rational design of potent small molecule SMARCA2/A4 (BRM/BRG1) degraders acting via the recruitment of FBXO22

Elisia Villemure, Robert L. Yauch, Joachim Rudolph…·Joyce Liu

This paper identifies a potent and specific SMARCA2/A4 degrader, G-6599, which works via FBXO22 recruitment and covalent conjugation, offering therapeutic potential.

2 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky