REV7 associates with ATRIP and inhibits ATR kinase activity
Megan Biller, Sara Kabir, Sarah Nipper…·Junya Tomida
This study identifies REV7 as a novel binding partner of ATRIP that inhibits ATR kinase activity and negatively regulates ATR signaling.
Author
University of North Carolina at CharlotteORCID 0000-0002-0813-5757Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Megan Biller, Sara Kabir, Sarah Nipper…·Junya Tomida
This study identifies REV7 as a novel binding partner of ATRIP that inhibits ATR kinase activity and negatively regulates ATR signaling.
Lilly F. Chiou, Gaith N. Droby, Deepika Jayaprakash…·Cyrus Vaziri
This study identifies RNF25's role in protecting DNA replication forks from degradation, independent of its ubiquitin signaling functions.
Kareen Pestana, Anthony Ford, Rei Rama…·Eugenia Lo
The paper investigates copy number variations of Plasmodium vivax genes in Duffy-positive and Duffy-negative Ethiopians, finding higher duplication rates in Duffy-positive samples.
Junya Tomida, Kei‐ichi Takata, Sarita Bhetawal…·Richard Dean Wood
This study identifies FAM35A as a REV7-associated protein that modulates DNA damage responses, showing altered expression in prostate cancer and resistance to PARP inhibitors in BRCA1-defective cells.