Christine A. Mills

This study identifies APOE interacting with COX-2 on lipid droplets, showing APOE3 promotes and APOE4 suppresses COX-2 activity and prostaglandin production.

This study identifies RNF25's role in protecting DNA replication forks from degradation, independent of its ubiquitin signaling functions.

This study examines the effects of sleep deprivation on synaptic vulnerability across developmental stages in mice, finding heightened sensitivity in juveniles and links to ASD risk.

This paper identifies and characterizes RA-0002034, a covalent inhibitor of CHIKV nsP2 protease, showing potent inhibition and selectivity against alphaviruses.

The paper identifies SMN complex binding partners and reveals conserved connections to chaperone systems, linking chaperone dysfunction to ALS and SMA.

The paper shows a monoclonal antibody against EZH2 cross-reacts with SAFB, highlighting the need for orthogonal assays in studying RNA-chromatin interactions.

This study identifies SAFB-associated RNAs in mouse embryonic stem cells and shows SAFB promotes gene expression by binding purine-rich regions in nascent transcripts.