Author

Pan Ma

Washington University in St. LouisORCID 0000-0002-0815-849XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:snRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Junedh AmruteiD· 3 shared Kory J. LavineiD· 3 shared Alekhya ParvathaneniiD· 1 shared Ana VillanuevaiD· 1 shared Andrea L. BredemeyeriD· 1 shared Andreas HerrlichiD· 1 shared Andrew L. KoenigiD· 1 shared Angeliki AsimakiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

Junedh AmruteORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyJACC Basic to Translational SciencePeer-reviewedMay 5, 2026

✦ In-depth digest

Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy

Vinay R. Penna, Junedh Amrute, Morgan Engel…·Stephen P. Chelko

Human arrhythmogenic cardiomyopathy hearts harbor a lesion niche of POSTN fibroblasts and NLRP3+ inflammatory macrophages; IL-1β neutralization in Dsg2-mutant mice reduced fibrosis, dysfunction, and ventricular ectopy.

11 citationstop 1%

humanmouse

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ImmunologyNature Cardiovascular ResearchPeer-reviewedApr 11, 2025

CD40 is an immune checkpoint regulator that potentiates myocardial inflammation through activation and expansion of CCR2+ macrophages and CD8 T-cells

Jesús Jiménez, Junedh Amrute, Pan Ma…·Kory J. Lavine

This study shows CD40 agonists promote myocardial inflammation by activating CCR2+ macrophages and CD8 T-cells, leading to heart failure.

21 citationstop 1%

mousebulk RNA-seq

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GenomicsbioRxivPreprintSep 11, 2022

Defining Cardiac Recovery at Single Cell Resolution

Junedh Amrute, Lulu Lai, Pan Ma…·Kory J. Lavine

The paper defines the cellular and transcriptional features of cardiac recovery using snRNA-seq, identifying RUNX1 downregulation as a key predictor and potential therapeutic target.

6 citations

humansnRNA-seq

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