Hitoyoshi Yasuo

The paper develops a toolkit of membrane-localising tags tested across ten animal species to identify effective signals for targeting proteins to the plasma membrane.

The paper examines transcriptional similarities between two neural lineages during ascidian embryogenesis and finds they cluster together despite limited shared transcriptional control.

The paper develops a mathematical model showing that geometry controls neural-epidermal cell fate in ascidian embryos through ERK signaling and Otx gene expression.

The paper identifies a Nodal/Eph signalling relay that controls the transition from apical constriction to apico-basal shortening during ascidian endoderm invagination, without affecting cell fate specification.