A cationic liposome-formulated Toll Like Receptor (TLR)7/8 agonist enhances the efficacy of a vaccine against fentanyl toxicity
Fatima Alamin Awad Alkareem Hamid, Nguyet‐Minh Nguyen Le, Daihyun Song, Hardik Hastibhai Amin, Linda D. Hicks, Sophia Bird, Karthik Siram, Brooke K. Hoppe, Borries Demeler, Jay T. Evans, David J. Burkhart, Marco Pravetoni
This paper shows that cationic liposome-formulated TLR7/8 agonist enhances fentanyl vaccine efficacy by improving immune activation and protecting against fentanyl-induced toxicity in rats.
Journal of Controlled Release · May 27, 2025Peer-reviewedImmunology