Immunologynpj VaccinesPeer-reviewed
The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine
Michael W. Crawford, Walid Abdelwahab, Karthik Siram…·Alec J. Hirsch
This paper develops a Powassan virus-like-particle (POW-VLP) vaccine adjuvanted with INI-4001, showing it enhances immunogenicity, reduces viral burden, and provides full protection in mice.
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