Adoptive Transfer of ILC2s into the Brain Reveals Tumor Homing in Glioblastoma: A Proof-of-Concept for Cellular Therapy
Lei P. Wang, Bidhan Bhandari, Sahar Emami Naeini, Breanna Hill, Hannah Mallalieu Rogers, Jules Gouron, Nayeli Perez-Morales, Aruba Khan, William Meeks, Ahmed A. Elmarakby, Nancy Young, Fernando Ĺ. Vale, Salman Ali, Gerald Wallace, Jack Chung-Kai Yu, , Babak Baban
This study shows that ILC2s can cross the BBB and home to glioblastoma tumors in mice, supporting adoptive transfer as a potential strategy for targeting CNS tumors.
bioRxiv · Dec 26, 2025 · PreprintImmunology