Author

Xinsheng Nan

Cardiff UniversityORCID 0000-0002-0865-7934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Mark HelmiD· 2 shared Tomasz Piotr JurkowskiiD· 2 shared Andrew H. Wang· 1 shared Annika Kötter· 1 shared Cassandra R. GlanfieldiD· 1 shared Christoph PlassiD· 1 shared Claudia I. DaviesiD· 1 shared Dieter WeichenhaniD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Mark HelmORCID

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2 papers

Recent·Most cited

Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase.

Manon Boulet, Guerric Gilbert, Yoan Renaud, Martina Schmidt, Emilie Auxerre-Plantié, Romane Bertrand, Xinsheng Nan, Tomasz Piotr Jurkowski, Mark Helm, Laurence Vandel, Lucas Waltzer

The paper investigates 6mA DNA modification in drosophila, finding it present at very low levels and not erased by TET, suggesting TET acts non-enzymatically.

bioRxiv · Sep 15, 2023 · PreprintMolecular Biology

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function

Mirunalini Ravichandran, Dominik Rafalski, Claudia I. Davies, Oscar Ortega‐Recalde, Xinsheng Nan, Cassandra R. Glanfield, Annika Kötter, Katarzyna Misztal, Andrew H. Wang, Marek Wojciechowski, Michał Rażew, Issam M. Mayyas, Olga Kardailsky, Uwe Schwartz, Krzysztof Zembrzycki, , Tomasz Piotr Jurkowski

The paper identifies sequence preferences of TET enzymes that target DNA demethylation to bHLH and bZIP transcription factor binding sites.

Science Advances · Sep 7, 2022Peer-reviewedMolecular Biology