Author

Tomasz Piotr Jurkowski

Cardiff UniversityORCID 0000-0002-2012-0240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:DNA methylation· 3 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

Mark HelmiD· 2 shared Phil OberackeriD· 2 shared Timothy A. HoreiD· 2 shared Xinsheng NaniD· 2 shared Alex Perkins· 1 shared Alexander James Phillips· 1 shared Andrew H. Wang· 1 shared Annika Kötter· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Mark HelmORCID

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4 papers

Recent·Most cited

Adenine methylation is very scarce in the drosophila genome and not erased by the Ten Eleven Translocation dioxygenase.

Manon Boulet, Guerric Gilbert, Yoan Renaud, Martina Schmidt, Emilie Auxerre-Plantié, Romane Bertrand, Xinsheng Nan, Tomasz Piotr Jurkowski, Mark Helm, Laurence Vandel, Lucas Waltzer

The paper investigates 6mA DNA modification in drosophila, finding it present at very low levels and not erased by TET, suggesting TET acts non-enzymatically.

bioRxiv · Sep 15, 2023 · PreprintMolecular Biology

Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function

Mirunalini Ravichandran, Dominik Rafalski, Claudia I. Davies, Oscar Ortega‐Recalde, Xinsheng Nan, Cassandra R. Glanfield, Annika Kötter, Katarzyna Misztal, Andrew H. Wang, Marek Wojciechowski, Michał Rażew, Issam M. Mayyas, Olga Kardailsky, Uwe Schwartz, Krzysztof Zembrzycki, , Tomasz Piotr Jurkowski

The paper identifies sequence preferences of TET enzymes that target DNA demethylation to bHLH and bZIP transcription factor binding sites.

Science Advances · Sep 7, 2022Peer-reviewedMolecular Biology

CONTAIN: An open-source shipping container laboratory optimisedfor automated COVID-19 diagnostics

Kenneth T. Walker, Matthew Donora, Anthony Thomas, Alexander James Phillips, Krishma Ramgoolam, Kjara S Pilch, Phil Oberacker, Tomasz Piotr Jurkowski, Rares Marius Gosman, Aubin Fleiss, Alex Perkins, Neil MacKenzie, Mark A. Zuckerman, Davide Danovi, Helene Steiner, Thomas Meany

The paper introduces CONTAIN, an automated RT-qPCR COVID-19 testing system based on a shipping container, achieving 2400 tests/day using open-source robotics and validated with synthetic and patient samples.

bioRxiv · May 20, 2020 · PreprintMolecular Biology

Bio-On-Magnetic-Beads (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation

Phil Oberacker, Peter Stepper, Donna M. Bond, Sven Höhn, Jule Focken, Vivien Meyer, Luca Schelle, Victoria J Sugrue, Gert‐Jan Jeunen, Tim Moser, Steven R. Hore, Ferdinand von Meyenn, Katharina Hipp, Timothy A. Hore, Tomasz Piotr Jurkowski

The paper introduces an open-source platform for high-throughput nucleic acid extraction and manipulation using magnetic beads, highlighting their cost-effectiveness and versatility.

PLoS Biology · Jan 10, 2019Peer-reviewedMolecular Biology