Author

Şevin Turcan

University Hospital BonnORCID 0000-0002-0885-5607Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

An D. Hoang· 1 shared Ashley V. SchwartziD· 1 shared Carrie Danielle HouseiD· 1 shared Cecilia GalloiD· 1 shared Christal Dyane SohliD· 1 shared Elene Albekioni· 1 shared Giovanni Quichocho· 1 shared Grace A. Wells· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

An D. Hoang

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Genetic and stochastic basis of phenotypic discordance in 16p11.2 mouse model deletion

Julián Taranda, Jana Velı́šková, Sukalp Muzumdar, Kith Pradhan, Kannan Umadevi Venkataraju, Ramesh Palaniswamy, Rhonda Drewes, Jianjun Sun, Nicolas Dross, Şevin Turcan, Jesse A Gillis, Libor Velı́šek, Pavel Osten

This study identifies two distinct subgroups of 16p11.2 deletion mice with different seizure susceptibility, circuit activity, brain structure, and gene expression profiles.

bioRxiv · Aug 4, 2026 · PreprintNeuroscience

Catalytically distinct IDH1 mutants tune phenotype severity in tumor models

Mowaffaq Adam Ahmed Adam, Mikella Robinson, Ashley V. Schwartz, Grace A. Wells, An D. Hoang, Elene Albekioni, Cecilia Gallo, Grace Chao, Joi L. Weeks, Giovanni Quichocho, Uduak Z. George, Carrie Danielle House, Şevin Turcan, Christal Dyane Sohl

This study shows that IDH1 R132Q mutants produce more D2HG than R132H mutants, leading to more aggressive tumors through distinct epigenetic and transcriptomic changes.

bioRxiv · Apr 22, 2024 · PreprintGenomics