Rhonda Drewes

This study identifies two distinct subgroups of 16p11.2 deletion mice with different seizure susceptibility, circuit activity, brain structure, and gene expression profiles.

This paper develops a tunable vascular dECM platform to study stiffness-driven vascular remodeling and identifies YAP and survivin as regulators of VSMC mechanotransduction.

This study identifies survivin as a mechanosensitive regulator linking ECM stiffness to GBM growth and matrisome remodeling, suggesting it as a therapeutic target.

The paper analyzes gene expression and protein networks in vascular injury models to show similarities with cardiovascular disease mechanisms.

The paper maps cell type densities in the mouse brain using single-cell imaging and computational analysis, revealing sex differences, shared signatures among brain regions, and associations between cell densities and anatomical functions.

The paper identifies distinct functional roles of pyramidal neuron types in cortical activity during decision-making tasks.

The paper provides a detailed cellular-resolution map of the mouse primary motor cortex, defining cell types and their connectivity.

The paper introduces LS-SOFI, a method combining light-sheet fluorescence microscopy and super-resolution optical fluctuation imaging for fast nanoscale-resolution imaging in 3D tissues.