Kannan Umadevi Venkataraju

This study identifies two distinct subgroups of 16p11.2 deletion mice with different seizure susceptibility, circuit activity, brain structure, and gene expression profiles.

The paper maps cell type densities in the mouse brain using single-cell imaging and computational analysis, revealing sex differences, shared signatures among brain regions, and associations between cell densities and anatomical functions.

The paper quantifies whole-brain XCI at single-cell resolution and finds a 60:40 paternal-to-maternal inactivation ratio that reduces disease penetrance in Fragile-X models.

The paper maps cerebellar pathways to forebrain regions using tracing viruses and quantitative analysis, revealing homologous networks linking cerebellar areas to sensory, motor, and associative forebrain targets.

The paper identifies distinct cortical-thalamic-striatal circuits within the parafascicular nucleus in mice, revealing heterogeneous neurons organized into parallel functional subcircuits.

This paper introduces a new light-sheet microscopy technique for high-resolution volumetric imaging of whole mouse brains.