Author

Osiris K. Lopez-Garcia

Texas A&M UniversityORCID 0000-0002-0885-9472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Daniel Paredes‐SabjaiD· 1 shared Fernando GiliD· 1 shared Josué Orozco· 1 shared Marjorie Pizarro‐GuajardoiD· 1 shared Nicolás Montes-BravoiD· 1 shared Pablo Castro-CórdovaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperMicrobiology

Daniel Paredes‐SabjaORCID

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1 paper

Recent·Most cited

Clostridioides difficile major toxins remodel the intestinal epithelia, affecting spore adherence/internalization into intestinal tissue and their association with gut vitronectin.

Pablo Castro-Córdova, Osiris K. Lopez-Garcia, Josué Orozco, Nicolás Montes-Bravo, Fernando Gil, Marjorie Pizarro‐Guajardo, Daniel Paredes‐Sabja

This study shows that C. difficile toxins TcdA and TcdB remodel fibronectin and vitronectin in intestinal tissue, enhancing spore adherence and internalization, which may contribute to disease recurrence.

bioRxiv · Jan 29, 2025 · PreprintMicrobiology