Author

Curtis Luscombe

University of BristolORCID 0000-0002-0893-7311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Eben JonesiD· 2 shared Laura RivinoiD· 2 shared Michaela GregorováiD· 2 shared Andrew D. DavidsoniD· 1 shared Chanh Quang Ho· 1 shared Chau Thi Xuan Nguyen· 1 shared Divya Diamond· 1 shared Duyen Huynh Thi Le· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Eben JonesORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight

Michaela Gregorová, Marianna Santopaolo, Lucy C. Garner, Rahma F. Hayati, Divya Diamond, Narayan Ramamurthy, Vi Thuy Tran, Nguyet Minh Nguyen, Kate J. Heesom, Nguyen Lam Vuong, Eben Jones, Mike Nsubuga, Curtis Luscombe, Hoa Thi My Vo, Chanh Quang Ho, , Laura Rivino

The paper identifies early T and NK-cell dysfunction in dengue patients that predicts severe disease, with obesity exacerbating these signatures.

Nature Communications · Jul 1, 2025Peer-reviewedImmunology

Impact of cryopreservation on immune cell metabolism as measured by SCENITH.

Curtis Luscombe, Eben Jones, Michaela Gregorová, Nicholas Jones, Laura Rivino

This study uses SCENITH to show cryopreservation affects immune cell metabolism, favoring glycolysis and impairing oxidative phosphorylation, but still allows for distinct metabolic profiling of cell subsets.

Oxford Open Immunology · Dec 17, 2024Peer-reviewedImmunology