Author

Caroline de Moraes de Siqueira

University of California, DavisORCID 0000-0002-0899-7410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Jeroen P. J. SaeijiD· 2 shared Abbigale J. Brown· 1 shared Andréa Rodrigues ÁvilaiD· 1 shared Baoyu CheniD· 1 shared Daniel A. KrameriD· 1 shared Emma Anne Johnston· 1 shared João Peçanha Schwartz· 1 shared Jörn CoersiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

Jeroen P. J. SaeijORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Toxoplasma gondii GRA66 prevents premature egress driven by the host phospholipase RARRES3, independently of RNF213

Caroline de Moraes de Siqueira, Stephanie Martinez-Beltran, Emma Anne Johnston, Jörn Coers, Jeroen P. J. Saeij

bioRxiv · Sep 15, 2026 · PreprintMicrobiology

Toxoplasma effector TgWIP hijacks dendritic cell actin and motility via Nck1/Grb2 and the WAVE complex

Pavel Morales, Daniel A. Kramer, Caroline de Moraes de Siqueira, Abbigale J. Brown, Lamba Omar Sangaré, Baoyu Chen, Jeroen P. J. Saeij

This study identifies TgWIP interactions with Nck1/Grb2 and the WAVE complex to reveal how Toxoplasma manipulates host cell actin dynamics and motility.

mBio · Oct 31, 2025Peer-reviewedMicrobiology

Unveiling the Unique Structure and Singular Function of the Histone Deacetylase 2 (TgHDAC2) of Toxoplasma gondii

Caroline de Moraes de Siqueira, João Peçanha Schwartz, Mariana Galvão Ferrarini, Mariana Sayuri Ishikawa Fragoso, Lysangela Ronalte Alves, Andréa Rodrigues Ávila, Tatiana de Arruda Campos Brasil de Souza, Sheila Cristina Nardelli

This study identifies TgHDAC2 in Toxoplasma gondii as a class I HDAC that deacetylates non-histone proteins, essential for cell cycle regulation and replication.

bioRxiv · Mar 21, 2025 · PreprintMicrobiology