Mariana Galvão Ferrarini

Unveiling the Unique Structure and Singular Function of the Histone Deacetylase 2 (TgHDAC2) of Toxoplasma gondii

This study identifies TgHDAC2 in Toxoplasma gondii as a class I HDAC that deacetylates non-histone proteins, essential for cell cycle regulation and replication.

Two distinct Trypanosoma eIF4F complexes co-exist, bind different mRNAs and are regulated during nutritional stress

The paper identifies two distinct eIF4F complexes in Trypanosoma cruzi that bind different mRNAs and show altered associations under nutritional stress.

Transcriptomic-based selection of reference genes for quantitative real-time PCR in an insect endosymbiotic model

The paper identifies stable reference genes for qRT-PCR in insect endosymbiotic models using transcriptomic data from Sitophilus oryzae.

Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in the cereal weevil Sitophilus spp.

The paper examines gene expression coordination between host and endosymbiont during the life cycle of the cereal weevil, identifying shared regulatory functions involved in symbiosis dynamics.

Investigating the human host - ssRNA virus interaction landscape using the SMEAGOL toolbox

The paper develops SMEAGOL, a tool to analyze RBP binding motif enrichment in ssRNA viral genomes, finding most are enriched or depleted in human RBP motifs, suggesting selection pressure on these interactions.

BrumiR: A toolkit for de novo discovery of microRNAs from sRNA-seq data.

BrumiR is a toolkit for de novo discovery of microRNAs from sRNA-seq data, achieving high recall and efficiency without a reference genome.

The transposable element-rich genome of the cereal pest Sitophilus oryzae

The paper presents the genome of Sitophilus oryzae, revealing high transposable element content and host-symbiont metabolic interactions.

Phenotypic and transcriptomic responses to stress differ according to population geography in an invasive species

The paper examines how invasive and non-invasive populations of D. suzukii respond to oxidative stress, finding differences in lifespan and gene expression that suggest rapid adaptation.

Genome-wide bioinformatic analyses predict key host and viral factors in SARS-CoV-2 pathogenesis

The paper uses bioinformatic analyses of RNA sequencing data to identify host and viral factors involved in SARS-CoV-2 pathogenesis, including differentially expressed genes and viral sequence variants linked to disease severity.