Silvia Anderle

The paper identifies nanovascular conduits formed by reticular fibroblasts that remove toxic proteins like tau and Abeta from the brain in mice and humans.

This study shows APOE4 mice have reduced vascular responsiveness and increased neuronal calcium signals in the visual cortex and hippocampus, suggesting APOE4 alters neurovascular function without causing severe deficits.

This study identifies chromosome 21 genes other than APP that modulate amyloid-β accumulation in Down syndrome mouse models.