David Attwell

The paper identifies nanovascular conduits formed by reticular fibroblasts that remove toxic proteins like tau and Abeta from the brain in mice and humans.

This study shows that remote ischaemic preconditioning protects the heart by releasing GLP-1, which relaxes cardiac pericytes and reduces no-reflow.

The paper shows that astrocyte Ca2+ activity regulates node of Ranvier length in white matter through adenosine signaling and NKCC1 activation, affecting axonal conduction speed.

This study examines how amyloidosis and ageing differentially affect microglial calcium activity in mouse brains, revealing distinct patterns in somatic and process Ca2+ responses.

This study identifies Nischarin as a regulator of GLT-1 surface expression and function in astrocytes, showing its role in glutamate uptake and neuroprotection.

This study shows that THIK-1 K+ channels in microglia regulate phagocytosis and synaptic pruning, with loss of THIK-1 increasing synaptic density in the hippocampus.

This study shows SARS-CoV-2 binding to ACE2 on pericytes enhances angiotensin II-induced cerebral capillary constriction via AT1 receptors, suggesting AT1 blockers may mitigate brain blood flow reduction in infection.

This study develops a fluorescent Aβ analogue to monitor glial cell phagocytosis of amyloid β in real time, showing microglia uptake exceeds astrocytes.

This study identifies the role of Arp2/3 and Cyfip1 in regulating microglial dynamics and suggests their involvement in neuropsychiatric diseases.

This study shows that amyloid β oligomers constrict human capillaries via pericyte signaling, reducing blood flow and contributing to Alzheimer’s disease pathology.