Author

Madison J. Bolejack

UCB Pharma (United States)ORCID 0000-0002-0911-2338Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Bart L. StakeriD· 2 shared Isabelle Q. PhaniD· 2 shared James C. MorrisiD· 2 shared Logan M. TilleryiD· 2 shared Audriy Jebet· 1 shared Bram Osterhout· 1 shared Brandy M. CalhouniD· 1 shared Brian N. DominyiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

Bart L. StakerORCID

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2 papers

Recent·Most cited

BiochemistryPLoS PathogensPeer-reviewedAug 1, 2024

Enolase inhibitors as therapeutic leads for Naegleria fowleri infection

Jillian E. Milanes, Victoria C. Yan, Cong-Dat Pham…·James C. Morris

This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.

20 citationstop 2%

humanmetabolomics

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Molecular BiologyPLoS ONEPeer-reviewedMar 24, 2021

Naegleria fowleri: protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein…·Wesley C. Van Voorhis A

The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.

28 citations

protein structureexperimental assay

𝕏 PostBluesky