Author
Clemson UniversityORCID 0000-0003-2515-5714Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jillian E. Milanes, Victoria C. Yan, Cong-Dat Pham…·James C. Morris
This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.
Kayleigh F. Barrett, Logan M. Tillery, Jenna Goldstein…·Wesley C. Van Voorhis A
The paper reports the structural determination of 19 N. fowleri proteins, identifying potential drug targets with structural differences from human homologs.
Isabelle Q. Phan, Christopher A. Rice, Justin K. Craig…·Peter John Myler
The paper identifies 59 compounds that inhibit Balamuthia mandrillaris growth and reconstructs its transcriptome to determine potential molecular targets for drug development.
Yijian Qiu, Vijay Shankar, Rooksana E. Noorai…·James C. Morris
The paper identifies a post-transcriptional regulatory element in the 3UTR of a lifecycle stage-regulated gene in Trypanosoma brucei that mediates glucose-responsive translational control.