Adriaan Verhelle

This paper uses variational autoencoders to predict DNA-methylation age and identifies biologically relevant features of ageing.

This study shows that LC3B phosphorylation by STK4 regulates FYCO1 binding and directional transport of autophagosomes, switching their movement from retrograde to anterograde under starvation conditions.

The paper identifies endosomal sorting pathways that drive the formation of mutant prion endoggresomes and shows that inhibiting this process can reduce axonal dysfunction.