Experimental evolution and functional genetics identify KIC1 as a determinant of reduced artemisinin susceptibility in Bangladeshi Plasmodium falciparum
Maisha Khair Nima, Nirjhar Bhattacharyya, Saiful Arefeen Sazed…·Angana Mukherjee
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International Centre for Diarrhoeal Disease ResearchORCID 0000-0002-0919-4652Unclaimed ORCID profile · follow to get notified of new preprints
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Maisha Khair Nima, Nirjhar Bhattacharyya, Saiful Arefeen Sazed…·Angana Mukherjee
Maisha Khair Nima, Nirjhar Bhattacharyya, Jungyoon Park…·Angana Mukherjee
The paper evaluates the impact of K13 mutations on artemisinin resistance and parasite fitness in Bangladeshi Plasmodium falciparum isolates, finding that R561H confers extreme resistance and fitness advantages.
Nikol Chantzi, Akshatha Nayak, Fotis A. Baltoumas…·Ilias Georgakopoulos‐Soares
Quadrupia identifies and characterizes G-quadruplex sequences across 108,449 genomes, revealing taxonomic patterns and experimentally validating key structures.