Experimental evolution and functional genetics identify KIC1 as a determinant of reduced artemisinin susceptibility in Bangladeshi Plasmodium falciparum
Maisha Khair Nima, Nirjhar Bhattacharyya, Saiful Arefeen Sazed…·Angana Mukherjee
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International Centre for Diarrhoeal Disease ResearchORCID 0000-0001-8330-5499Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
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Maisha Khair Nima, Nirjhar Bhattacharyya, Saiful Arefeen Sazed…·Angana Mukherjee
Tristan P. W. Dennis, Amélie Vantaux, Kevin C. Kobylinski…·Brandyce St. Laurent
The paper provides genomic resources for malaria vector surveillance in Southeast Asia, revealing population structure and resistance regions in Anopheles dirus.
Maisha Khair Nima, Nirjhar Bhattacharyya, Jungyoon Park…·Angana Mukherjee
The paper evaluates the impact of K13 mutations on artemisinin resistance and parasite fitness in Bangladeshi Plasmodium falciparum isolates, finding that R561H confers extreme resistance and fitness advantages.
Hasan Mohammad Al‐Amin, Narayan Gyawali, Melissa C. Graham…·Gregor J. Devine
The paper creates and characterizes a Wolbachia-infected Aedes aegypti strain with a Dhaka genetic background, showing it has reduced dengue virus transmission potential and comparable fitness to wild-type mosquitoes.
Hidayat Trimarsanto, Roberto Amato, Richard D. Pearson…·Sarah Auburn
The paper develops a molecular barcode and online tool to identify and map imported Plasmodium vivax infections using SNP analysis and machine learning.
Claire Louise Jeffries, Michaël Luciano Tantely, Përparim Kadriaj…·Thomas Walker
This study examines genetic and microbial diversity of Culex tritaeniorhynchus across multiple continents, finding high genetic and microbial variation and evidence of Wolbachia and insect-specific viruses.