Cancer BiologybioRxivPreprint
SMYD3 protein degraders in HPV-negative head and neck squamous cell carcinoma.
Jawad Akhtar, Sai Reddy Doda, William Moore…·Vassiliki Saloura
This study develops SMYD3 proteolysis targeting chimeras (PROTACs) for HPV-negative head and neck squamous cell carcinoma, showing effective SMYD3 degradation and reduced oncogenic activity.
DOI 10.64898/2026.09.28.754983