Developmental BiologybioRxiv
SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β-cells
Romina J. Bevacqua, Jonathan Y. Lam, Heshan S. Peiris…·Seung K. Kim
This study shows that SIX2 and SIX3 regulate functional maturity and fate of human pancreatic β-cells, with SIX2 affecting insulin processing and glucose sensing, and SIX3 influencing gene expression patterns.
45 citations