Teija C. M. Frame

This study shows that TGF-β signaling in CD4 T cells regulates the balance between protective and regulatory immunity in visceral leishmaniasis by controlling T cell expansion, differentiation, and effector function.

This study examines CD4+ T cell responses in visceral leishmaniasis using single-cell RNA sequencing, revealing transcriptional heterogeneity and regulatory mechanisms affecting immune function.

This study investigates the role of NKG7 in CD4+ and CD8+ T cells during malaria, showing protective and cell-intrinsic functions in different infection models and human infections.