Author
University of CambridgeORCID 0000-0002-0952-2396Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
5 papers
Recent·Most cited
Cherif Badja, Sophie Momen, Ching Chiek Koh…·Serena Nik‐Zainal
This study investigates neurodegeneration in Xeroderma pigmentosum using stem cell-derived neurons, identifying endoplasmic reticulum stress and UPS dysfunction as key factors and developing an early detection assay.
Xueqing Zou, Ching Chiek Koh, Arjun Scott Nanda…·Magdalena Zarowiecki
The paper identifies gene-specific mutational signatures caused by replication errors and endogenous DNA damage using CRISPR-Cas9 knockouts and whole-genome sequencing.
Sushmita Sridhar, Sally Forrest, Iain Robert Louis Kean…·Stephen G. Baker
The paper describes the development of a validated SARS-CoV-2 diagnostic workflow in an academic laboratory to support local screening during the pandemic.
Gloria Alvarado, Sarah R. Holland, Jordan DePerez-Rasmussen…·Nathan T. Mortimer
The paper analyzes parasitoid venom evolution and function through bioinformatic methods to understand mechanisms of host manipulation.
Jonathan S. Brammeld, Mia Petljak, Iñigo Martincorena…·Ultan McDermott
This paper describes a method to identify drug resistance mutations in cancer using genome-wide chemical mutagenesis and next-generation sequencing, enabling the discovery of both known and novel resistance mechanisms.