Coralie Viollet

This study identifies PTX3 as a key antifibrotic factor secreted by fibroblasts that modulates epithelial repair in acute injury and exacerbates damage in chronic injury.

The paper systematically evaluates the metabolic and transcriptional effects of SLC superfamily members, identifying new substrates and functional groups.

This study investigates ligand-specific AXL signaling in IPF, showing GAS6 promotes basal cell proliferation while PROS1 inhibits it, with implications for therapeutic targets.

The paper identifies O-GlcNAcylation of JUNB as a regulator of promoter accessibility in metabolic genes, driving aberrant epithelial lineage in IPF.

In Silico Treatment evaluates animal models for disease relevance by simulating gene expression changes in humans, identifying suitable models and drug effects.

The paper identifies rare protein-coding variants influencing plasma protein levels in 50,829 UK Biobank participants using exome-wide association studies.

This paper identifies five new genetic risk loci for Lewy body dementia through whole-genome sequencing and shows shared risk profiles with Alzheimer’s and Parkinson’s disease.

The paper identifies common LRRK2 locus variation associated with survival in progressive supranuclear palsy, linking it to gene expression regulation and suggesting therapeutic implications for tauopathies.