Stacie M. Anderson

PI3Kdelta promotes T cell effector differentiation and plasticity during chronic infection

This study shows that activated PI3Kdelta reduces TCF-1+ stem-like CD8+ T cells but promotes effector differentiation and viral control during chronic infection.

Divergence between transcriptomes and chromatin accessibility during differentiation from a bipotential progenitor cell population to erythroblasts and megakaryocytes

The paper compares transcriptomes and chromatin accessibility in MEP, ERY, and MEG cells to reveal divergence in gene regulation during differentiation.

Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism

The paper compares dopaminergic neurons from siblings with Gaucher disease to investigate genetic factors contributing to Parkinsonism.

Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

This study identifies conserved and species-specific cis-regulatory elements in human and mouse blood cells using integrative epigenomic analysis and clustering.

Effects of sheared chromatin length on ChIP-seq quality and sensitivity

This study investigates how chromatin shearing affects ChIP-seq quality and shows that sonication levels significantly impact signal quality and specificity for different transcription factors.