Author

Yukun Ou

Dana-Farber Cancer InstituteORCID 0000-0002-1014-5890Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Gunsagar Singh GulatiiD· 2 shared Ji-Heui SeoiD· 2 shared Matthew L. FreedmaniD· 2 shared Rashad NawfaliD· 2 shared Ze Zhang· 2 shared Zhenjie JiniD· 2 shared Adam G. SowalskyiD· 1 shared Andrew J. AguirreiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Gunsagar Singh GulatiORCID

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2 papers

Recent·Most cited

Histone modifications define distinct nucleosome positions in cell-free DNA

Yukun Ou, Gunsagar Singh Gulati, Caroline F. Tyndall, Medha Pandey, Ji-Heui Seo, Ze Zhang, Zhenjie Jin, Garyoung Gary Lee, Rashad Nawfal, Taylor A. Hoggood, Sadia D. Shahbazi, John Ludwig, Ziwei Zhang, Élio Ibrahim, Gaelle Nafeh, , Sylvan C. Baca

This paper identifies histone modification-associated nucleosome positions in cfDNA that correlate with tumor fraction and cancer state across multiple cancers.

bioRxiv · Oct 28, 2026 · PreprintCancer Biology

Integrated inference of cancer gene expression from cell-free plasma chromatin

Gunsagar Singh Gulati, Damien Vasseur, Rashad Nawfal, Shahabeddin Sotudian, Karl Semaan, Marc Eid, Ji-Heui Seo, Noa Phillips, John Canniff, Hunter Savignano, Surya B. Chhetri, Zhenjie Jin, Yukun Ou, Mohamed Amine Bani, Gwo‐Shu Mary Lee, , Matthew L. Freedman

APEX infers cancer gene expression from plasma cfChIP-seq data, outperforming existing methods and enabling subtype classification and biomarker identification.

bioRxiv · Feb 19, 2026 · PreprintGenomics