Neurosciencenpj Parkinson s DiseasePeer-reviewed
Interaction of G2019S LRRK2 and metabolic syndrome in a two-hit mouse model of Parkinson's disease: LRRK2-driven systemic depletion of pyrimidine nucleosides
Yue Ma, Madalynn L. Erb, Kayla A. Sipple…·Darren J. Moore
The paper investigates how G2019S LRRK2 interacts with metabolic syndrome in a mouse model of Parkinson's disease, showing systemic nucleotide and energy metabolism disruptions and mitochondrial dysfunction.
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