Author

Yingda Jiang

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-1032-5605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1

Frequent Co-Authors

Alexander J. LazariD· 2 shared Angela D. BhallaiD· 2 shared Davis R. IngramiD· 2 shared Emily Zhi-Yun KeungiD· 2 shared Keila E. TorresiD· 2 shared Khalida WaniiD· 2 shared Kumaren Anand· 2 shared Kunal RaiiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alexander J. LazarORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 26, 2026

Spatially-Resolved Multiomic Atlas of Leiomyosarcoma Identifies Two Clinically Relevant Epigenetically-Driven Cell States

Ryan A. Denu, Zhao Zheng, Yingda Jiang…·Kunal Rai

This study identifies two epigenetically distinct cell states in leiomyosarcoma using single-nucleus multiome sequencing and spatial transcriptomics, linking them to clinical outcomes and therapeutic vulnerabilities.

DOI 10.64898/2026.05.22.726988

humanscRNA-seq

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Cancer BiologybioRxivPreprintNov 23, 2025

ATRX Loss Predicts Poor Outcomes and Reveals a Therapeutic Vulnerability to TEAD Inhibition in Soft Tissue Sarcomas

Ryan A. Denu, Anand Kamal Singh, Yingda Jiang…·Kunal Rai

This study shows ATRX loss in sarcomas correlates with poor outcomes and identifies TEAD inhibition as a potential therapy for ATRX-deficient tumors.

DOI 10.1101/2025.11.23.689992

humanbulk RNA-seq

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Genetic & Genomic MedicineNature GeneticsPeer-reviewedDec 1, 2024

Distinctive cross-ancestry genetic architecture for age-related macular degeneration

Bryan R. Gorman, Georgios Voloudakis, Robert P. Igo…·Srinivas V. Goverdhan

This study identifies 63 AMD risk loci across multiple ancestries, highlighting ancestry-dependent genetic heterogeneity and potential therapeutic targets.

58 citationstop 1%

humanGWAS summary statistics

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