Author

Zhao Zheng

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Assay:ATAC-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

Kunal RaiiD· 4 shared Veena KochatiD· 4 shared Alexander J. LazariD· 3 shared Davis R. IngramiD· 3 shared Emily Zhi-Yun KeungiD· 3 shared Keila E. TorresiD· 3 shared Khalida WaniiD· 3 shared Neeta SomaiahiD· 3 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

Kunal RaiORCID

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Author profile →

5 papers

Recent·Most cited

A population genomic resource for Drosophila pseudoobscura

Yesbol Manat, Zhao Zheng, Camryn Kritzell, Christopher A. Gonzales, Richard P. Meisel

The paper presents a population genomic resource for Drosophila pseudoobscura, analyzing 60 sequenced genomes to study chromosomal structure and genetic variation across the species' geographic range.

G3 Genes Genomes Genetics · Aug 1, 2026Peer-reviewedGenomics

Spatially-Resolved Multiomic Atlas of Leiomyosarcoma Identifies Two Clinically Relevant Epigenetically-Driven Cell States

Ryan A. Denu, Zhao Zheng, Yingda Jiang, Suresh Satpati, Veena Kochat, Kumaren Anand, Danh D. Truong, Andrew R. Lynch, William I. Padron, Davis R Ingram, Khalida Wani, Diana Shamsutdinova, Angela D. Bhalla, Sharon M. Landers, Ravin Ratan, , Kunal Rai

This study identifies two epigenetically distinct cell states in leiomyosarcoma using single-nucleus multiome sequencing and spatial transcriptomics, linking them to clinical outcomes and therapeutic vulnerabilities.

bioRxiv · May 26, 2026 · PreprintCancer Biology

Reprogramming of Cellular Plasticity via ETS and MYC Core-regulatory Circuits During Response to MAPK Inhibition in BRAF-mutant Colorectal Cancer

Hey Min Lee, Zhao Zheng, Alexey V. Sorokin, Chi Wut Wong, Stefania Napolitano, Saikat Chowdhury, Preeti Kanikarla Marie, Anand Kamal Singh, Veena Kochat, Christopher Aaron Bristow, Sanjana Srinivasan, Michael D. Peoples, Emre Arslan, Jumanah Yousef Alshenaifi, Oscar Eduardo. Villarreal, , Scott Kopetz

This study shows BET + MAPK inhibitors improve efficacy against BRAFV600E CRC by inducing epigenetic reprogramming and cellular plasticity through enhancer dynamics disruption.

Clinical Cancer Research · May 8, 2026Peer-reviewedCancer Biology

Spatially-resolved single cell atlas of liposarcoma reveals lineage hierarchies, immune niches, and regulatory circuits

Ryan A. Denu, Veena Kochat, Zhao Zheng, Suresh Satpati, Danh D. Truong, Emre Arslan, Corey Weistuch, Margarita Divenko, Manrong Wu, William I. Padron, Davis R Ingram, Khalida Wani, Wei-Lien Wang, Sharon M. Landers, Hannah C. Beird, , Kunal Rai

This study uses single-nucleus multiome sequencing and spatial transcriptomics to analyze liposarcoma subtypes, revealing distinct cellular states, immune features, and gene regulatory circuits.

bioRxiv · Mar 25, 2026 · PreprintCancer Biology

ATRX Loss Predicts Poor Outcomes and Reveals a Therapeutic Vulnerability to TEAD Inhibition in Soft Tissue Sarcomas

Ryan A. Denu, Anand Kamal Singh, Yingda Jiang, Zhao Zheng, Davis R. Ingram, Khalida Wani, Rossana Lazcano, Madison P. Ginn, Kumaren Anand, Bishal K. Singh, Jackson C. Ballard, Veena Kochat, Biji Chatterjee, William I. Padron, Sharon M. Landers, , Kunal Rai

This study shows ATRX loss in sarcomas correlates with poor outcomes and identifies TEAD inhibition as a potential therapy for ATRX-deficient tumors.

bioRxiv · Nov 23, 2025 · PreprintCancer Biology